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New Diabetes Subtype Found in African and Black American Youth, Challenging Traditional Diagnosis
New Diabetes Subtype Found in African and Black American Youth, Challenging Traditional Diagnosis
Sputnik Africa
New Diabetes Subtype Discovered in African and African American Youth, Challenging Traditional Diagnosis 22.07.2025, Sputnik Africa
2025-07-22T17:09+0200
2025-07-22T17:09+0200
2025-07-22T18:03+0200
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New Diabetes Subtype Discovered in African and African American Youth, Challenging Traditional DiagnosisKey discovery: A study published in The Lancet Diabetes & Endocrinology has uncovered a non-autoimmune form of type 1 diabetes (T1D) affecting many young people in Sub-Saharan Africa—and even a portion of Black Americans.What’s different?Unlike classic T1D, which is autoimmune, 65% of African participants in the study lacked islet autoantibodies—key markers for autoimmune diabetes. These youth likely have a distinct, non-autoimmune subtype of T1D, requiring different diagnostic and treatment approaches.US comparison:Researchers also found that 15% of Black Americans with T1D showed similar patterns—autoantibody-negative and genetically distinct from the typical autoimmune form—unlike their white counterparts.Why it matters:This research, spanning Cameroon, Uganda, South Africa, and the US, could lead to more accurate diagnoses and personalized treatment strategies for populations previously underserved by conventional models.“Alternative causes must be considered in this group of individuals, and understanding the drivers of this subtype might offer new insights into prevention and treatment,” the study read.
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New Diabetes Subtype Discovered in African and African American Youth, Challenging Traditional Diagnosis
Key discovery: A study published in The Lancet Diabetes & Endocrinology has uncovered a non-autoimmune form of type 1 diabetes (T1D) affecting many young people in Sub-Saharan Africa—and even a portion of Black Americans.
Unlike classic T1D, which is autoimmune, 65% of African participants in the study lacked islet autoantibodies—key markers for autoimmune diabetes. These youth likely have a distinct, non-autoimmune subtype of T1D, requiring different diagnostic and treatment approaches.
Researchers also found that 15% of Black Americans with T1D showed similar patterns—autoantibody-negative and genetically distinct from the typical autoimmune form—unlike their white counterparts.
This research, spanning Cameroon, Uganda, South Africa, and the US, could lead to more accurate diagnoses and personalized treatment strategies for populations previously underserved by conventional models.
“Alternative causes must be considered in this group of individuals, and understanding the drivers of this subtype might offer new insights into prevention and treatment,” the study read.