Earlier in the day, Aksenov said that Ukraine attempted to strike infrastructure facilities in the Krasnogvardeisky district of the Republic of Crimea.
He also stated that emergency services and other relevant officials were on the scene to tackle possible consequences.
"As a result of an enemy drone attack on the Krasnogvardeisky district, a detonation occurred at an ammunition depot. According to preliminary data, there is no destruction and casualties," Aksenov wrote on his Telegram channel.
Evacuation orders have been issued for people residing within a 5-kilometer (3.1-mile) radius within the site.
Rail service on Crimean railways has been suspended to "minimize risks," Aksenov added.
The Crimean head expressed the hope that the effects of the incident would be eliminated in a short time, adding that all up-to-date information would be posted on the website of the regional transport ministry and other official outlets.