At least nine activists of the South African ruling party died in a car accident, the local media News 24 reported.
The bus they were in overturned on the highway in the province of KwaZulu-Natal, according to an official statement.
The activists were returning from South Africa's city of Durban from an ANC rally held the day before.
Another 10 people were injured and are in critical condition. The causes of the accident are under investigation.